Methyl-Guard - 180 Capsules | Thorne

Supports methylation 

The body's methylation process is key to maintaining a healthy level of homocysteine, as well as to multiple other biochemical processes. Methyl-Guard was the first nutritional supplement on the market to support homocysteine metabolism and healthy methylation using nutrients in their active, tissue-ready forms.

Methylation – the addition of a methyl group (CH3 – one carbon attached to three hydrogens) to another molecule – is an essential and vital biochemical process in the body involved in multiple biochemical pathways involving neurotransmitters, detoxification, cardiovascular health, eye health, muscle health, bone health, and redox balance. A number of specific nutrients are necessary for the process of methylation to occur effectively.

A number of biochemical imbalances that raise the level of homocysteine can be addressed by supplementing with appropriate nutrient cofactors. For example, folic acid (as L-5-methyltetrahydrofolate), vitamin B12 (as methylcobalamin), and betaine (trimethylglycine) help recycle homocysteine to the amino acid methionine, while the recycling of homocysteine into the beneficial amino acids cysteine and taurine is facilitated by pyridoxal 5'-phosphate (the active form of vitamin B6).Studies have shown these nutrients help maintain a normal level of homocysteine in the blood.

Because homocysteine levels can be higher in individuals in which the enzymatic reaction that converts folic acid to the active methyl donor L-5-methyltetrahydrofolate (5-MTHF) does not function properly, Methyl-Guard contains 400 mcg of active 5-MTHF per capsule.

• Betaine contributes to normal homocysteine metabolism
• Vitamin B6 contributes to normal homocysteine,  energy-yielding , protein and glycogen metabolism
• Vitamin B6 contributes to normal psychological function
• Vitamin B6 contributes to normal red blood cell formation
• Vitamin B6 contributes to the normal function of the immune & nervous system
• Vitamin B6 contributes to the reduction of tiredness and fatigue
• Vitamin B6 contributes to the regulation of hormonal activity
• Vitamin B6 contributes to normal cysteine synthesis
• Folate contributes to maternal tissue growth during pregnancy
• Folate contributes to normal amino acid synthesis
• Folate contributes to normal blood formation
• Folate contributes to normal homocysteine metabolism
• Folate contributes to normal psychological function
• Folate contributes to the normal function of the immune system
• Folate contributes to the reduction of tiredness and fatigue
• Folate has a role in the process of cell division
• Supplemental folic acid intake increases maternal folate status. Low maternal folate status is a risk factor in the development of neural tube defects in the developing foetus.
• Vitamin B12 contributes to normal functioning of the nervous & immune system
• Vitamin B12 contributes to normal psychological function
• Vitamin B12 contributes to normal energy-yielding & homocysteine metabolism
• Vitamin B12 contributes to normal red blood cell formation
• Vitamin B12 contributes to the reduction of tiredness and fatigue
• Vitamin B12 has a role in the process of cell division