Methyl-Guard Plus - 90 Capsules | Thorne

Methyl-Guard Plus® Details

Various conditions and stressors can have an adverse impact on the body’s methylation cycle. Nutrient deficiencies, environmental exposures, and other aspects of a modern lifestyle can cause inefficient methylation. In addition, approximately 60 percent of U.S. adults have a genetic variation that makes it difficult for their methylation cycle to function optimally.

Thorne’s Methyl-Guard Plus features betaine (trimethylglycine), methylated vitamin B12 (methylcobalamin) and folate (5-MTHF), as well as the active forms of vitamins B2 and B6, for providing efficient nutritional support for the body’s methylation challenges.*

Benefits of Thorne’s Methyl-Guard Plus:

Nutritional support for individuals who have MTHFR gene mutations*

Enhanced cellular energy production fights fatigue*

Helps maintain a healthy homocysteine level in the blood, which supports cardiovascular, cognitive, and bone health*

Promotes fat metabolism and lean body composition*

Supports neurotransmitter production – natural chemicals that play an important role in nervous system functions, like attention, focus, mood, and sleep*

Promotes liver detoxification of many substances, including hormones like estrogen*

Why is methylation important:

Methylation is a simple reaction where a small molecule known as a “methyl group” is transferred from one substance to another. Methylation significantly impacts many biochemical reactions in the body and plays a beneficial role in:

Cardiovascular health

Cellular energy production

Fat metabolism

Neurological function

DNA production

Liver detoxification processes

Eye health

Histamine balance

Who can benefit from Thorne's Methyl-Guard Plus:

Individuals with mutations to MTHFR and other genes that adversely affect methylation*

Aging individuals wanting to support their cardiovascular, cognitive, and metabolic health*

Women seeking support for estrogen metabolism and bone health*

Individuals wanting nutritional support for fat metabolism and maintenance of a healthy body composition*

Anyone with limited consumption of methylation-supportive foods like green leafy vegetables, legumes, and cruciferous vegetables

Features of Thorne's Methyl-Guard Plus:

Betaine, also known as trimethylglycine, is a superior methyl donor 

The methylated forms of vitamin B12 (methylcobalamin) and folate (5-MTHF) benefit individuals with certain gene mutations*

Active forms of vitamins B2 and B6 – key cofactors in methylation processes

B vitamins in their active, tissue-ready forms means your body gets the greatest benefit with the least additional work*

Robust methylation support in fewer capsules per day than Thorne’s original Methyl-Guard®

• Betaine contributes to normal homocysteine metabolism
• Riboflavin contributes to normal energy-yielding metabolism
• Riboflavin contributes to normal functioning of the nervous system
• Riboflavin contributes to the maintenance of normal mucous membranes, skin, vision & red blood cells
• Riboflavin contributes to the normal metabolism of iron
• Riboflavin contributes to the protection of cells from oxidative stress
• Riboflavin contributes to the reduction of tiredness and fatigue
• Vitamin B6 contributes to normal homocysteine,  energy-yielding , protein and glycogen metabolism
• Vitamin B6 contributes to normal psychological function
• Vitamin B6 contributes to normal red blood cell formation
• Vitamin B6 contributes to the normal function of the immune & nervous system
• Vitamin B6 contributes to the reduction of tiredness and fatigue
• Vitamin B6 contributes to the regulation of hormonal activity
• Vitamin B6 contributes to normal cysteine synthesis
• Folate contributes to maternal tissue growth during pregnancy
• Folate contributes to normal amino acid synthesis
• Folate contributes to normal blood formation
• Folate contributes to normal homocysteine metabolism
• Folate contributes to normal psychological function
• Folate contributes to the normal function of the immune system
• Folate contributes to the reduction of tiredness and fatigue
• Folate has a role in the process of cell division
• Supplemental folic acid intake increases maternal folate status. Low maternal folate status is a risk factor in the development of neural tube defects in the developing foetus.
• Vitamin B12 contributes to normal functioning of the nervous & immune system
• Vitamin B12 contributes to normal psychological function
• Vitamin B12 contributes to normal energy-yielding & homocysteine metabolism
• Vitamin B12 contributes to normal red blood cell formation
• Vitamin B12 contributes to the reduction of tiredness and fatigue
• Vitamin B12 has a role in the process of cell division